Welcome to the Dustin Baldridge lab
Our lab studies the genetic basis of rare Mendelian disorders and develops high-throughput cell-based assays and functional genomics techniques to experimentally characterize the effects of clinically observed variants. We also use genome sequencing and informatics approaches to increase the usability of genetic data at the bedside and improve clinical care.
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Please contact Dustin with any questions.
Dustin Baldridge, MD, PhD
Dustin Baldridge, MD, PhD, is a board-certified pediatrician conducting full-time translational genomics research at Washington University in St. Louis, where he is an Assistant Professor of Pediatrics in the Division of Genetics and Genomic Medicine. Baldridge is committed to helping children with underlying genetic disorders receive a molecular diagnosis.
He completed his combined MD/PhD training at Baylor College of Medicine, postgraduate training in Pediatrics at Washington University School of Medicine, and one year of service as a Chief Resident at St. Louis Children’s Hospital. As a successfully funded NHGRI K08 awardee focused in the areas of genomic medicine and functional genomics, he is leading a team that is solving a fundamental problem in human genetics, namely the overwhelming number of variants of uncertain significance (VUS) generated via exome and genome sequencing.
Baldridge also serves as a co-investigator for the Washington University Model Organism Screening Center (wuMOSC) of the Undiagnosed Diseases Network (UDN), where his responsibilities include assessing candidate gene variants from a human genetics perspective and assisting in the identification of the most appropriate model organism (worm, fly, or fish) in which to model the variant.