Our lab studies the genetic basis of rare Mendelian disorders and develops high-throughput cell-based assays and functional genomics techniques to experimentally characterize the effects of clinically observed variants. We also use genome sequencing and informatics approaches to increase the usability of genetic data at the bedside and improve clinical care.
Dustin Baldridge Lab
Illuminating the functional impact of genetic variants in rare Mendelian disorders
Dustin Baldridge, MD, PhD
Principal Investigator
Dustin Baldridge, MD, PhD, is a board-certified pediatrician and WashU Medicine Assistant Professor of Pediatrics, specializing in translational genomics research. His work focuses on diagnosing children with genetic disorders at a molecular level. After completing his MD/PhD at Baylor College of Medicine, he underwent postgraduate training in the WashU Medicine Department of Pediatrics. Baldridge also served as chief resident at St. Louis Children’s Hospital for a year.
He is a funded NHGRI K08 awardee, leading a team to address the challenge of variants of uncertain significance (VUS) in human genetics derived from sequencing efforts. Baldridge is also a co-investigator at the WashU Medicine Model Organism Screening Center (wuMOSC) within the Undiagnosed Diseases Network (UDN). His role there involves evaluating gene variants from a human genetics standpoint and selecting suitable model organisms—such as worms, flies, or fish—to study these variants
Come learn with us…
Are you interested in joining our team?
Please contact Dustin with any questions.
With generous support from:
National Human Genome Research Institute
Undiagnosed Diseases Network
Children’s Discovery Institute
Institute of Clinical and Translational Sciences
Intellectual and Developmental Disabilities Research Center
